Should You Stop Blending Bananas with Berries? Inside the Surprising Science of Smoothie Nutrition

Uncover simple swaps that keep your drinks nutrient-packed without losing flavor.

By Sneha Tete, Integrated MA, Certified Relationship Coach
Created on

Should You Rethink How You Make Your Smoothie?

Smoothies have become a staple of healthy eating, blending together fruits, vegetables, protein, and more into a convenient, vibrant package. For many, bananas and berries are must-have ingredients — they create creamy, flavor-rich bases that spell the start of many mornings. But recent research suggests the choice to blend these two favorites together could quietly sap your smoothie of some of its most important health benefits. Should you stop mixing bananas and berries? Let’s examine the latest science and get practical advice on the best ways to blend your morning shake.

Bananas and Berries: A Classic Smoothie Duo

It’s easy to see why bananas and berries have long been popular in smoothies:

If you want to delve deeper into the incredible health benefits of bananas, you should explore our comprehensive guide to banana nutrition and its best uses. This resource will give you insight into how this superfood can enhance your smoothies and overall health.
  • Bananas provide thickness, offer natural sweetness, and make the texture creamy and filling.
  • They’re rich in fiber, potassium, and vitamin B6, with modest amounts of magnesium, vitamin C, and even a touch of protein.
  • Berries (blueberries, strawberries, blackberries) are packed with antioxidants, especially compounds called flavanols, as well as vitamin C and fiber.
  • Together, they create a nutrient-dense, deliciously sweet combination that’s easy to love.

Despite these nutritional highlights, the latest research has cast some doubt on whether this classic pairing truly delivers all the anticipated health perks.

The Science: What Happens When You Blend Bananas and Berries?

A recent peer-reviewed study published in Food & Function challenged long-held smoothie wisdom. The research found that blending bananas with certain berries — specifically those high in a class of compounds called flavanols — can significantly reduce the amount of flavanols your body absorbs.

To ensure you’re maximizing the nutritional impact of your smoothie, check out our nutritionist-approved guide on what not to mix with protein powder. This guide will equip you with knowledge to avoid common pitfalls while blending.

What Are Flavanols and Why Do They Matter?

Flavanols are a group of plant compounds (a type of flavonoid) found abundantly in foods like cocoa, apples, grapes, berries, mangoes, pineapple, and pears. They’re linked to improvements in cardiovascular health, blood pressure regulation, cognitive function, and may even reduce inflammation and the risk of chronic disease.

  • Clinical studies connect flavanol intake with better heart and brain health outcomes.
  • Berries are one of the best smoothie-friendly sources of flavanols.

The Hidden Enzyme: Polyphenol Oxidase (PPO) in Bananas

The culprit behind the nutrient loss? Polyphenol oxidase (PPO), an enzyme that bananas contain in high concentrations. This enzyme causes fruit browning — think of how banana slices quickly turn brown after being cut — but it also plays an unseen role when mixed with other ingredients.

To discover which fruits are the healthiest choices for your smoothies, make sure to read our nutritionists' guide to the healthiest fruits. This guide will help you make informed decisions about what to include for maximum benefit.
  • When high-PPO fruit (like banana) is blended with high-flavanol ingredients (such as berries), the PPO enzyme breaks down the flavanols during smoothie preparation — before you even take a sip.
  • This chemical reaction means that your body ultimately absorbs far fewer flavanols from the finished smoothie.

The Study: What Did Researchers Find?

The study measured the levels of flavanols in participants’ blood and urine after consuming three types of drinks:

  • Mixed berry smoothie
  • Banana smoothie
  • Control group (flavanol capsule)

Key findings include:

  • Consuming a mixed-berry smoothie without banana resulted in similar flavanol absorption as the control.
  • Adding a banana to the smoothie reduced flavanol absorption by 84% — meaning only 16% of the beneficial flavanols made it into the participants’ bloodstream.
  • This striking reduction was attributed directly to the action of the PPO enzyme in banana.
  • The effect was generalizable to both men and women, as the enzymatic reaction occurs during blending, not digestion. Sex differences do not impact the result.
For an in-depth understanding of pairing foods for optimal nutrition, you should check out our top 10 nutritious food combos that boost your health. This valuable information will guide your smoothie choices for enhanced nutrient absorption.

Should You Stop Using Bananas in Smoothies?

The logical question: If bananas are breaking down the health-boosting compounds in your smoothie, should you skip them entirely? The short answer is: No. Bananas still deliver many healthy nutrients and remain an excellent smoothie ingredient, but it’s best not to pair them with berries or other high-flavanol fruits if your goal is maximizing antioxidant intake.

To enhance your smoothies with high-protein options, explore our guide to high-protein fruits that can power up your diet. These insights will help you create shakes that are not only delicious but also satiating.

Best Smoothie Pairings for Bananas

If you love what bananas add to a smoothie, consider combining them with ingredients lower in flavanols or those less susceptible to PPO breakdown. Try these combinations:

  • Banana + nut butters (peanut, almond, cashew) for a protein- and healthy-fat-rich smoothie.
  • Banana + papaya, avocado, or pear — these fruits also have higher PPO, which means less risk of further flavanol loss.
  • If you crave a fruit blend, try pairing banana with pineapple, orange, or mango — these options are less impacted by PPO and create a tropical flavor profile.

Making the Most of Your Berry Smoothies

If it’s berries you’re after for their flavanol punch — and you only use bananas for their creamy, sweet texture — you have alternatives:

For a deeper dive into high-fiber options, check out our list of the best high-fiber fruits to boost your health. Incorporating these fruits can not only help with digestion but also keep your smoothies nutritious and satisfying.
  • Add Greek yogurt (for thick texture and added protein).
  • Mango — similar creaminess and mild sweetness.
  • Oats or chia seeds for added viscosity and fiber.
  • A spoonful of honey can make up for banana’s sweetness.
  • For added richness, try avocado in a berry smoothie (its healthy fats add body).

By adjusting your recipe, you can easily create berry-rich smoothies that preserve their nutrient potential.

Deep Dive: Understanding Flavanols, PPO, and Their Interaction

Fruit/IngredientPPO LevelFlavanol ContentBest Use in Smoothies
BananaHighLow-ModerateCombine with nut butters, avoid with high-flavanol fruits if possible
Berries (Blueberry, Strawberry, Blackberry)LowHighBest used alone or with yogurt, avoid bananas for max antioxidative effect
Papaya, Avocado, PearHighLow-ModerateCan be blended with banana, not ideal for boosting antioxidants
Pineapple, Orange, MangoLowModerateGood to combine with banana for sweetness and flavor variety

This table breaks down which ingredients are best paired for targeting different nutrition goals.

Why Does This Matter? The Role of Nutrition Synergy

Nutrition is more than just adding different healthy foods together; the way ingredients interact can affect what your body actually absorbs. The banana-berry interaction is just one example of these “synergy” effects that aren’t always intuitive:

  • Preparation matters — blending and combining can change nutrient absorption.
  • Nutrients can compete or interfere — some block the uptake of others, some amplify.
  • Raw vs. cooked, or blending vs. juicing, also changes the nutritional profile of foods.

For those specifically consuming smoothies for their antioxidant value — especially those aiming to support heart or brain health — ingredient combinations become more than just a question of taste.

Expert Tips for Healthier Smoothie Blending

Registered dietitians and nutrition experts offer practical strategies for more effective smoothie making:

  • Identify your smoothie goals — are you seeking antioxidants, protein, satiety, or simply flavor?
  • Don’t skip bananas if you love them, but pick your pairings wisely. Use with nut butters, or low-flavanol fruits for a filling shake.
  • For a berry-focused antioxidant boost, leave out banana and use Greek yogurt, mango, or avocado for creaminess.
  • If you use bananas mostly for sweetness, add a bit of honey or maple syrup as a replacement. For texture, try frozen mango, oats, or cottage cheese.
  • Be open to experimentation — smoothies blend best when tailored to your preferences and nutrition needs.

Frequently Asked Questions (FAQs)

Should everyone avoid blending bananas and berries?

No, you don’t have to avoid them entirely unless your priority is maximizing flavanol (antioxidant) intake. Bananas and berries are both nutritious, but the combination reduces the absorption of specific beneficial antioxidants.

Can I still eat bananas and berries together if I don’t blend them?

Yes. The enzymatic breakdown of flavanols by PPO happens primarily during blending, so eating whole fruits in combination is unlikely to have the same drastic reduction in flavanol absorption.

Are bananas unhealthy now?

Absolutely not. Bananas remain a great source of fiber, potassium, and many vitamins, and are perfectly healthy as a snack or as part of other smoothies. It’s the specific pairing with high-flavanol ingredients in smoothies that’s problematic if flavanols are your goal.

What are the best substitutions if I miss the banana texture in a berry smoothie?

For creaminess: use Greek yogurt, mango, avocado, oats, or silken tofu. For extra sweetness, a touch of honey, dates, or ripe pear can help.

Does freezing bananas affect the enzyme problem?

Freezing slows down enzyme activity but does not fully inactivate PPO. Thus, frozen bananas can still react with flavanols when blended, although possibly at a slightly reduced rate.

Takeaway: Smarter Smoothie Pairings for Maximum Nutrition

Blending bananas and berries together may not be the antioxidant powerhouse we believed, but both fruits can still have a place in your healthy lifestyle. With a few adjustments — like swapping banana for mango or yogurt in your berry smoothie, or pairing banana with nut butters and lower flavanol fruits — you can craft delicious shakes that harness the full potential of their ingredients.

Awareness of ingredient interactions can help you get the most out of every smoothie, tailored to your wellness priorities. Happy blending!

Sneha Tete
Sneha TeteBeauty & Lifestyle Writer
Sneha is a relationships and lifestyle writer with a strong foundation in applied linguistics and certified training in relationship coaching. She brings over five years of writing experience to thebridalbox, crafting thoughtful, research-driven content that empowers readers to build healthier relationships, boost emotional well-being, and embrace holistic living.

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