Dermarolling Pre & Post Care Protocol: Step-by-Step Scientific Guide for Safe, Effective Results
A clear roadmap to preparing and protecting your skin for optimal microneedling recovery.

Dermarolling, also known as microneedling, has become a widely popular skin care treatment for addressing acne scars, wrinkles, stretch marks, and overall skin rejuvenation. However, its effectiveness and safety depend heavily on following rigorous pre and post care protocols. This article provides a comprehensive, evidence-based guide on every aspect of dermarolling preparation, procedure, and recovery, ensuring optimal outcomes and minimal risks.
Table of Contents
- Introduction to Dermarolling
- How Dermarolling Works
- Pre-Care Protocol
- Dermarolling Step-by-Step Procedure
- Post-Care Protocol
- Contraindications and Risks
- Frequently Asked Questions (FAQs)
- Summary Table: Quick Reference Guide
Introduction to Dermarolling
Dermarolling, or microneedling, is a minimally invasive cosmetic procedure that uses a roller covered with tiny needles to create micro-injuries on the skin’s surface. This controlled trauma triggers the body’s natural healing response, stimulating collagen and elastin production. The procedure helps to reduce the appearance of acne scars, fine lines, hyperpigmentation, stretch marks, and improves overall skin texture and radiance. Dermarollers vary in needle length and design, and protocols must be tailored to individual skin conditions and desired outcomes.
How Dermarolling Works
- Microneedles penetrate the epidermis, creating hundreds of controlled micro-injuries.
- This stimulates a wound healing response, releasing growth factors and signaling fibroblast activity.
- Collagen and elastin synthesis leads to skin thickening, improved texture, and diminished scarring.
- Channels formed allow for enhanced absorption of topical products post-treatment.
Pre-Care Protocol
Thorough pre-treatment preparation is vital to reduce the risk of infection, irritation, and adverse events. Follow the guidelines below to maximize your results:
1. Medication and Topical Product Restrictions
- Avoid Accutane (isotretinoin) for at least 6 months prior to treatment.
- Discontinue topical products that sensitize skin—such as retinoids, antibiotics, exfoliating acids (AHA/BHA), salicylic acid, hydroquinone, and benzoyl peroxide—5–7 days pre-procedure.
- Cease anti-inflammatory drugs (ibuprofen, Motrin, Advil) 3 days prior, as they can inhibit the essential inflammatory process involved in healing.
- Avoid blood-thinning supplements (aspirin, Omega-3, fish oil, vitamin E) up to 1 week before treatment to minimize bruising.
2. Skin Preparation and Protection
- Postpone dermarolling if you have active acne, infections, or open wounds on the target area.
- No waxing, depilatory creams, electrolysis on the area within 5–7 days pre-procedure.
- Avoid unprotected sun exposure, sunburn, and laser/IPL treatments for 2 weeks before treatment.
- If prone to cold sores, start an antiviral medication 2 days prior and on treatment day (by prescription).
- Avoid shaving the day of the procedure; if necessary, shave the area the day before, unless dense hair is present.
3. Optional Pre-Conditioning
- Use pre-conditioning skincare as recommended by your provider (e.g., vitamin C serum, niacinamide) for 4–6 weeks prior for improved outcomes.
- Optimize nutrition—collagen supplements and a diet rich in amino acids support healing and collagen synthesis.
4. Hygiene Measures
- Arrive with a clean face, free from makeup, sunscreen, and lotions.
- Disinfect your dermaroller in 70% isopropyl alcohol for 5–10 minutes before use.
Dermarolling Step-by-Step Procedure
1. Disinfect the Dermaroller
Soak the dermaroller in 70% isopropyl alcohol for 5–10 minutes and air-dry.
2. Facial Cleansing
- Wash with a gentle, pH-balanced cleanser.
- If using needles longer than 0.5 mm, wipe skin with 70% alcohol prior to rolling.
- Inspect for wounds; do not proceed if any lesions are present.
3. Numbing Cream (Optional)
- Apply numbing cream, especially for needle lengths above 1.0 mm.
- Follow manufacturer instructions, and remove completely before rolling.
4. Rolling Technique
- Mentally divide the face into sections for systematic coverage.
- Start with one direction (vertical), rolling 4 times, lifting the roller after each pass to avoid tram track scarring.
- Repeat in the perpendicular direction (horizontal).
- Avoid the delicate eye area; be cautious near the orbital bone.
- Do not roll diagonally unless advised by a professional.
- Use gentle, even pressure—do not overwork any area.
5. Rinsing and Immediate Aftercare
- Rinse the face gently with water only post-microneedling; avoid cleansers and any actives.
- Apply a calming mask (e.g., hyaluronic acid) for 5–10 minutes and then moisturizer.
6. Dermaroller Cleaning and Storage
- Wash the dermaroller in unscented detergent mixed with water using a plastic container. Swish without scraping the needles.
- Disinfect again in fresh 70% alcohol for 10 minutes, then store in a sterile case.
Post-Care Protocol
Post-dermarolling protocol is essential for skin recovery, preventing infection, and ensuring the full benefits of treatment:
Day 1–3: Immediate Aftercare
- Expect a sunburn-like effect: Redness, swelling, tightness, and mild sensitivity are normal.
- Wash the skin gently with a mild cleanser and cool water, using hands only. Pat dry, no earlier than 4 hours post-procedure.
- Moisturize skin with a simple, fragrance-free moisturizer (e.g., Cetaphil, Aquaphor). Over-moisturizing can delay peeling; balance hydration as needed.
- No active ingredients—avoid retinoids, vitamin C, harsh exfoliants, acids, benzoyl peroxide, etc.
- Do not use anti-inflammatory medications (NSAIDs) for at least 1 week as they may interfere with healing. Use Tylenol for pain relief only, if needed.
- Avoid ice packs, arnica, or bromelain—these can blunt the critical inflammation for collagen synthesis.
- Avoid strenuous exercise, excessive sweating, hot showers, steam rooms, saunas, jacuzzis for 24–48 hours.
- Do not sleep on treated areas; elevate your head to minimize swelling.
Day 4 and Beyond: Ongoing Recovery
- Redness and sensitivity gradually subside over several days. Small bruises from aggressive treatments may appear, especially with PRP, and can last up to a week.
- Swelling usually resolves within 2–4 days.
- After 24 hours, use only oxygen-permeable or mineral-based makeup if necessary. Avoid regular make-up until the skin has healed.
- Begin using a broad-spectrum SPF 30+ daily and reapply every 2 hours when outdoors, starting 24 hours post-treatment.
- Avoid sun tanning and direct exposure for 2 weeks.
Dietary Recommendations for Optimal Healing (Optional)
- Consume collagen supplements, bone broth soups, and foods rich in omega-3 fatty acids.
- Incorporate tart cherry juice (no sugar) for anti-inflammatory benefit.
- Avoid dairy, refined sugars, and wheat during the initial healing period.
Long-Term Care and Maintenance
- Resume active skincare only after skin is fully healed (typically 7–10 days post procedure).
- Repeat dermarolling sessions no sooner than 4 weeks apart.
- Maintain a gentle daily skin routine focusing on hydration, barrier repair, and sun protection.
Contraindications and Risks
Who Should Avoid Dermarolling?
- Pregnancy—not recommended due to unknown safety.
- Active skin infections or inflammation (e.g., infected acne, cold sores, eczema flare-ups).
- Cystic acne or nodular acne in treatment area.
- Keloid scars—microneedling may exacerbate keloid formation.
- Allergies to topical anesthetics like lidocaine, or severe reactions to skincare ingredients.
- Recent sunburn or laser/IPL procedures.
- Mole, wart, or actinic keratosis on treatment area—do not roll over these lesions.
Potential Side Effects
- Temporary redness, mild swelling, and sensitivity
- Pinpoint bleeding (especially with needles >1.0 mm)
- Small bruises, transient skin peeling
- Rare risk of infection if proper hygiene isn’t followed
- Tram track scarring from improper technique
- Hyperpigmentation in darker skin tones if aftercare or sun protection is neglected
Frequently Asked Questions (FAQs)
Q: Can I use actives (retinoids, vitamin C, acids) after dermarolling?
A: No. Active ingredients should be avoided for at least 7 days post-procedure. Use only gentle hydrating products during the healing phase.
Q: How often should I dermaroll?
A: Schedule treatments every 4–6 weeks, allowing ample time for skin recovery and collagen synthesis between sessions.
Q: Is dermarolling safe for all skin types?
A: While dermarolling is safe for most skin types, those with darker skin should be cautious of post-inflammatory hyperpigmentation and consult with a professional before treatment.
Q: What needle length is best for at-home use?
A: For home use, needles between 0.2–0.5 mm are safest. Professional treatments may use longer needles, which require expert technique and post-care.
Q: How will my skin look right after microneedling?
A: Expect redness, mild swelling, and sensitivity (like a sunburn) that typically resolves in 2–4 days.
Q: What should I do if I suspect infection or a reaction?
A: Seek medical advice immediately if you notice pus, increased warmth, severe pain, or lesions on the skin.
Summary Table: Quick Reference Guide
Stage | Essential Steps | Key Restrictions |
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Pre-Care |
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Procedure |
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Post-Care |
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Final Recommendations
- Always follow pre- and post-care rigorously to maximize results and minimize risks.
- Consult a dermatologist or licensed professional for personalized advice, especially if you have complex skin conditions.
- Consistency in aftercare—especially sun protection and barrier maintenance—is key to long-term skin regeneration.
References
- https://www.healthline.com/health/beauty-skin-care/dermarolling-how-it-works-before-and-after
- https://yelenalapidusmd.com/med-spa/pre-post-treatment-instructions/
- https://skinmdchicago.com/blog/what-should-you-avoid-before-and-after-microneedling/
- https://www.theclinicoregon.com/content/uploads/2020/04/Microneedling-Pre-and-Post-Instructions.pdf
- https://hob-aesthetics.com/microneedling-aftercare-tips-for-best-results/
- https://www.youtube.com/watch?v=kkVJIuNKEOU
- https://www.skinbylovely.com/pre-and-post-care/micro-needling/
- https://www.virginiafacialplasticsurgery.com/operation-instructions/microneedling-post-operative-instructions
- https://skincancer-specialists.com/blog/what-to-expect-after-microneedling-5-things-to-avoid/
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