Cold & Flu Management Strategies for Adults With Autoimmune Diseases
Advice to strengthen immunity and ease symptoms for people with immune disorders.

Cold & Flu Management in Autoimmune Adults
Adults living with autoimmune diseases face unique challenges when it comes to preventing, identifying, and treating the common cold and flu. Because their immune systems are dysregulated—or sometimes suppressed by essential medications—seasonal viruses can cause more severe symptoms, heightened risk of complications, and longer recovery periods. This guide synthesizes expert insights to deliver a comprehensive resource for managing cold and flu season in autoimmune adults.
Table of Contents
- Understanding Autoimmune Disease & Viral Risks
- Best Prevention Strategies
- Nutrition and Lifestyle Support
- Supplements: What’s Helpful and What to Avoid
- Vaccinations and Immune Response
- Managing Symptoms at Home
- When To Seek Medical Help
- Frequently Asked Questions
- Conclusion
Understanding Autoimmune Disease & Viral Risks
Autoimmune diseases, like rheumatoid arthritis, lupus, or Crohn’s disease, occur when the immune system mistakenly attacks the body’s own tissues. These conditions may be treated with immunosuppressant medications, further complicating the body’s response to viral infections such as the cold or flu. In this context:
- Immune dysfunction makes it difficult for the body to distinguish between harmless self-cells and dangerous invaders.
- Flu and cold infections can trigger flares, worsen symptoms, and prolong recovery periods in autoimmune adults.
- Inflammation, already heightened in autoimmune conditions, increases in response to viral infections and can cause additional tissue damage.
- Immunosuppressive therapies such as corticosteroids or biologics reduce the body’s ability to fight off infection.
Viral illnesses can sometimes even trigger new autoimmune conditions or flares in established ones .
Best Prevention Strategies
Preventing illness is particularly important for those with autoimmune diseases. Here are foundational strategies:
- Hand Hygiene: Wash your hands thoroughly and frequently, especially after public exposure or before eating.
- Limit Exposure: Avoid crowded spaces during peak cold and flu season, and consider wearing masks when necessary.
- Practice Respiratory Etiquette: Cover your coughs and sneezes; avoid touching your face.
- Sanitize Surfaces: Regularly disinfect high-touch objects and shared surfaces.
- Stay Informed: Monitor community transmission rates and adjust activities accordingly.
- Good Sleep: Prioritize quality sleep for optimal immune resilience.
- Moderate Exercise: Engage in activities like yoga, stretching, brisk walking, or tai chi.
- Stress Management: Chronic stress can exacerbate inflammation and suppress immune function.
These measures reduce not only your risk of acquiring cold and flu but can also decrease the intensity and duration of symptoms if you do become ill.
Nutrition and Lifestyle Support
A balanced diet and healthy lifestyle are essential components of immune support, especially for autoimmune patients facing increased infection risks.
Recommended Foods for Immune Support
- Bone Broth: Rich in amino acids that support gut and immune health.
- Vitamin A sources: Grass-fed dairy, wild-caught fish, and organic meats promote barrier integrity and immune function.
- Fermented Foods & Probiotics: Low-sugar yogurt, kefir, naturally fermented veggies, and probiotic supplements encourage healthy gut flora that is critical for robust immunity.
- Vitamin D: Safe sun exposure and possibly supplements, especially for those taking steroids, which can deplete vitamin D.
- Zinc: Found in pumpkin seeds, oysters, and naturally-raised meats to support cell-mediated immunity.
- Vitamin C: Promotes a balanced immune response. Include citrus, kiwi, peppers, and greens.
Fluids and Hydration
- Drink water, bone broth, herbal teas, and chicken soup regularly, even before getting sick.
- Avoid excessive sugar and alcohol, which can suppress immune function and dehydrate.
Other Lifestyle Tips
- Prioritize Rest: Healing and immune regulation thrive during adequate, restorative sleep.
- Consistent, gentle movement: Overexertion can worsen symptoms and increase infection risk, but mild exercise supports overall well-being.
Supplements: What’s Helpful and What to Avoid
Supplements are a double-edged sword for autoimmune adults. Some can be helpful when tailored to specific needs and medical guidance—others are best avoided due to risk of overstimulating the immune response or interacting with medications.
Supplements to Consider (With Physician Supervision)
- Vitamin C
- Vitamin D
- Zinc
- Probiotics (if approved by a healthcare provider)
- Quercetin (an antioxidant that may reduce inflammation)
Always discuss with your doctor before starting any new supplement, as some may not be suitable for your personal medication regimen or specific autoimmune condition.
Supplements to Avoid or Use With Caution
Supplement | Reason for Caution |
---|---|
Elderberry | Potentially overstimulates immune system; contraindicated with many autoimmune conditions. |
Echinacea | May trigger increased immune activity; interactions with immunosuppressive meds. |
Astragalus | Similar risk of excessive immune activation. |
St. John’s Wort | Dangerous drug interactions, especially with immunosuppressants. |
Each person’s needs are unique—what’s safe for one may be risky for another.
Vaccinations and Immune Response
Vaccination is a crucial protective measure for adults with autoimmune conditions:
- Flu Shot: Strongly recommended unless advised otherwise by your physician. The inactivated flu shot (not the live nasal vaccine) is safest for most.
- Pneumonia Vaccine: Critical due to heightened risk of pneumonia-related complications (especially for those with inflammatory arthritis or those on immunosuppressive medications). Two types of pneumonia vaccines exist; consult your doctor for personalized recommendations.
- Timing and Medication: Some immunosuppressants (like methotrexate) can blunt vaccine response. In certain cases, pausing these medications for a short time may improve vaccine efficacy (under doctor’s supervision).
Live vaccines are typically contraindicated in immune-suppressed adults. Always consult your rheumatologist or immunologist before receiving any vaccine.
Managing Symptoms at Home
If you do get sick, focus on:
- Rest and hydration—sleep as much as the body needs and drink fluids often. Dehydration can lead to more severe complications.
- Nourishment: Continue eating supportive foods; soups and broths are gentle and hydrating.
- Fever, aches, or pains: Acetaminophen (paracetamol) is often preferred, as NSAIDs can sometimes worsen autoimmune flares (ask your physician about preferred medications).
- Saline sprays or rinses for sinus congestion.
- Monitor symptoms closely for signs of complications or prolonged illness.
When To Seek Medical Help
Autoimmune adults should reach out to healthcare providers immediately if they experience:
- Shortness of breath or difficulty breathing
- Persistent high fever (especially beyond 3 days)
- Chest pain or palpitations
- Confusion, persistent vomiting, or inability to hydrate
- New or rapidly worsening autoimmune symptoms (e.g., severe joint swelling, rash, muscle weakness)
- Symptoms that do not improve after a week or worsen after initial improvement
Your doctor may advise temporarily stopping certain immunosuppressive medications during active infections—never do this without physician supervision.
Frequently Asked Questions (FAQs)
Are immune-boosting supplements safe in autoimmune disease?
Not all. Some popular “immune-boosters,” like elderberry, echinacea, and astragalus, may overstimulate the immune system and cause flares. Always consult your specialist before taking any supplement.
Should autoimmune adults get the flu shot every year?
Yes, unless your specialist says otherwise. The inactivated flu shot is recommended for most adults with autoimmune conditions.
Does a cold or flu always trigger an autoimmune flare?
No, but illness increases the risk. Support your body through rest, nutrition, and prompt care to reduce flare likelihood.
Is it safe to keep taking my autoimmune medication when I’m sick?
Speak to your healthcare provider. Some medications may need to be paused during acute infections, but this decision should always be made by your doctor.
What if my symptoms get worse or don’t resolve?
Contact your physician—autoimmune adults are at greater risk for complications and may need more aggressive monitoring or treatment.
Conclusion
Adopting a personalized, well-informed approach is the surest path to successful cold and flu management for adults with autoimmune diseases. Prevention via hygiene, nutrition, and vaccination are foundational, while close symptom monitoring and early medical intervention help minimize complications. With the right strategies and a collaborative partnership with healthcare providers, most autoimmune adults can navigate cold and flu season with confidence and resilience.
References
- https://caplanhealthinstitute.com/how-autoimmune-patients-stay-healthy-during-cold-and-flu-season/
- https://holplus.co/how-viruses-and-the-flu-affect-autoimmune-diseases/
- https://www.bondwithhealth.com/blog/8-tips-for-cold-flu-with-autoimmune
- https://creakyjoints.org/living-with-arthritis/cold-flu-season-inflammatory-arthritis/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3024156/
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1558386/full
- https://pmc.ncbi.nlm.nih.gov/articles/PMC1070843/
- https://my.clevelandclinic.org/health/diseases/21624-autoimmune-diseases
- https://www.autoimmuneinstitute.org/articles/how-do-cold-temperatures-affect-autoimmune-disease
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