Top 7 Benefits Of Jiaogulan For Health And Its Side Effects

A centuries-old adaptogen shown to support metabolism, immunity, and stress resilience.

By Medha deb
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What Is Jiaogulan?

Jiaogulan (Gynostemma pentaphyllum) is a climbing herbaceous vine belonging to the cucumber and gourd family. Known as the “immortality herb”, southern ginseng, five-leaf ginseng, and sweet tea vine, this plant thrives in the mountainous regions of southern China as well as areas of Thailand, Japan, Vietnam, and Korea. Unlike true ginseng, jiaogulan is not fruit-bearing. Instead, its serrated leaves are prized for their use in traditional medicine, particularly as a nourishing herbal infusion or tea.

Steeped in centuries of traditional Asian medicine, jiaogulan has a reputation for enhancing vitality, endurance, and longevity. Various communities, especially in China’s Guizhou province, believe that regular consumption of jiaogulan supports a longer, healthier life. Its unique adaptogenic and antioxidant compounds help the body manage stress and may offer broad protective health effects.

Key Takeaways

  • Jiaogulan is a traditional Asian herb valued for its multifaceted health benefits.
  • The plant is used to aid weight management, reduce cholesterol and glucose levels, and treat respiratory ailments.
  • Jiaogulan’s adaptogenic properties help counteract stress and support overall vitality.
  • It should not be used before surgery due to a possible effect on blood clotting.

Active Compounds & Properties

Jiaogulan contains a rich array of saponins called gypenosides, which are believed to account for many of its health effects. These gypenosides bestow the herb with potent antioxidant, anti-inflammatory, and adaptogenic properties. Adaptogens are compounds that help the body maintain homeostasis and resist the damaging effects of physical, environmental, and emotional stress.

In addition to saponins, jiaogulan is also a source of flavonoids, vitamins, minerals, and dietary fiber. Together, these components contribute to the plant’s broad therapeutic profile, particularly its ability to regulate metabolic and immune functions.

A Comparison: Jiaogulan vs. Panax Ginseng

AttributeJiaogulanPanax Ginseng
FamilyCucumber/gourd (Cucurbitaceae)Araliaceae (true ginseng)
Key CompoundsGypenosides (saponins)Ginsenosides (saponins)
Main UseAdaptogenic, metabolic supportStimulant, adaptogen
Traditional ReputationImmortality herb, stress reliefEnergy, stamina, immune health
Geographic OriginChina and Southeast AsiaKorea and Northeast Asia

Top 7 Health Benefits of Jiaogulan

1. May Aid in Diabetes Management

Early research suggests jiaogulan may help regulate blood sugar levels by improving insulin sensitivity. Animal and limited human studies indicate the herb’s unique gypenosides may facilitate glucose uptake by cells, potentially supporting diabetes care and providing a mild blood-sugar-lowering effect. However, robust clinical data in humans remain limited, and anyone with diabetes should consult their physician before adding jiaogulan to their regimen.

2. May Help Combat Obesity

Jiaogulan’s potential role in weight management is linked to its capacity to regulate metabolic processes. A key mechanism involves activation of the AMP-activated protein kinase (AMPK) pathway, which helps stimulate fat burning and energy metabolism. Research, including controlled human trials, has demonstrated mild reductions in body weight and fat mass. Combined with its adaptogenic benefits, jiaogulan may be beneficial as part of a weight loss program.

3. Helps Lower Cholesterol Levels

Gypenosides in jiaogulan may contribute to lowering harmful LDL cholesterol and improving favorable HDL cholesterol ratios. Animal and preliminary human trials have reported reductions in overall cholesterol and triglyceride levels, supporting cardiovascular wellness. Nevertheless, these findings are not fully conclusive for all populations, and further research is warranted.

4. May Help Relieve Stress

Jiaogulan is classified as an adaptogen, a group of herbs reputed for their stress-fighting properties. Recent clinical studies suggest supplementation with jiaogulan extract can reduce anxiety proneness and help the body better cope with chronic psychological stress. By modulating stress hormones like cortisol, it supports relaxation and emotional stability.

5. Can Help Treat Insomnia

The adaptogenic nature of jiaogulan also creates a positive ripple effect by aiding sleep. Adaptogens may help resolve pain and inflammation—common sleep disruptors thus promoting a more restful, undisturbed slumber. Historically, herbalists have recommended jiaogulan tea to those experiencing insomnia tied to stress or pain.

6. May Boost Immune System Function

Jiaogulan’s antioxidants, vitamins, and minerals may enhance immune resilience. Traditional use and some animal studies indicate that the herb helps the immune system adapt to challenges, potentially reducing the incidence or severity of seasonal illnesses. While promising, more clinical research is needed to confirm immune benefits in humans.

7. Supports Cardiovascular Health

In addition to cholesterol-lowering effects, jiaogulan helps regulate nitric oxide in the body, which in turn supports vascular relaxation and healthy blood pressure. The herb’s broad spectrum of antioxidants may also shield the heart from oxidative stress and cellular damage.

Other Traditional Uses of Jiaogulan

  • Treating minor colds, coughs, and bronchial conditions
  • Alleviating fatigue and supporting long-term stamina
  • Promoting liver and digestive health

Despite these broad traditional uses, modern scientific evidence remains limited, so jiaogulan should not replace established medical therapies.

How to Use Jiaogulan

  • Jiaogulan is most commonly consumed in the form of herbal tea by steeping leaves in hot water for up to 10 minutes.
  • Powdered or encapsulated jiaogulan supplements are also available.
  • There is no standardized recommended daily dose—usage varies based on product and individual health status.
  • Most sources advise not exceeding a few weeks of continuous daily use without the guidance of a healthcare professional.

Who Can Use Jiaogulan?

Jiaogulan is generally safe for healthy adults seeking natural support for stress, metabolism, or vitality. It is not recommended for children, pregnant or breastfeeding individuals, those on blood thinners, or people facing imminent surgery. Due to potential blood thinning and immune system effects, consultation with a physician is advised before regular use.

Possible Side Effects & Safety Considerations

  • Digestive upset (nausea, diarrhea, stomach pain)
  • Possible increase in bleeding risk (avoid before surgery)
  • Interference with blood pressure and immune-modulating medications
  • Potential allergic reactions in sensitive individuals

If any adverse effects develop, discontinue use and seek medical advice promptly. Keep in mind that long-term safety data for jiaogulan is lacking.

FAQ: Frequently Asked Questions About Jiaogulan

What is jiaogulan most commonly used for?

It is consumed mainly for its adaptogenic benefits, to help manage stress, support metabolic health (including cholesterol and glucose regulation), and promote general vitality.

How do you prepare jiaogulan tea?

Steep 1-2 teaspoons of dried jiaogulan leaves in hot water for 5–10 minutes. Strain and drink. This can be repeated 1–2 times daily, as desired.

Is jiaogulan related to ginseng?

Although sometimes called “southern ginseng,” jiaogulan is botanically unrelated to true ginseng plants but shares some similar adaptogenic properties.

Are there any drug interactions to watch out for?

Jiaogulan can interact with blood thinners, antihypertensive drugs, and immune suppressants. Always consult with a healthcare professional if you are taking medication.

Can jiaogulan help with weight loss?

Preliminary research suggests it may modestly support weight reduction when combined with diet and exercise, but conclusive clinical evidence is limited.

Infographic Summary: Benefits of Jiaogulan

  • Rich in antioxidants, dietary fiber, vitamins, and minerals
  • Supports heart health, relieves stress, improves sleep, may help prevent cancer
  • May aid in diabetes management and weight loss
  • Best enjoyed as a tea; excess may cause side effects

Precautions & Warnings

  • Avoid before surgery: May increase bleeding risk.
  • Pregnancy & breastfeeding: Not enough evidence for safety—avoid use.
  • Drug interactions: Consult a doctor if you take medications for blood pressure, clotting, or immunity.
  • Discontinue use if you experience nausea, diarrhea, or other adverse reactions.

Conclusion

Jiaogulan is an ancient herbal remedy renowned for its adaptogenic and metabolic benefits. While traditional use and early scientific research highlight many promising effects for diabetes, cholesterol, weight management, stress relief, and immune support, conclusive evidence is still emerging. As with any herbal supplement, moderation and medical guidance are key to safe use.

Medha Deb is an editor with a master's degree in Applied Linguistics from the University of Hyderabad. She believes that her qualification has helped her develop a deep understanding of language and its application in various contexts.

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