9 Best Wrinkle Fillers of 2024, According to Dermatologists
Discover the top wrinkle fillers—both topical and injectable—to smooth, plump, and rejuvenate your skin safely and effectively.
If you’re seeking the best wrinkle fillers to achieve smoother, firmer, and plumper skin, both topical and injectable options abound in 2024. Whether you want instant results before an event, longer-lasting plumping for deeper lines, or needle-free alternatives that really deliver, expert guidance ensures you’ll find a solution to match your skin type, lifestyle, and expectations. Below, discover top-rated wrinkle fillers—including innovative serums, creams, and the most in-demand injectables—thoroughly reviewed for efficacy, safety, and ease of use.
What Are Wrinkle Fillers?
Wrinkle fillers, also known as dermal fillers, are products designed to reduce the appearance of fine lines and wrinkles. They can be:
- Injectable fillers, delivered under the skin by a medical professional (e.g., hyaluronic acid injections).
- Topical fillers, like serums and creams, applied to the skin’s surface to hydrate, plump, and smooth lines temporarily.
The best choice depends on your goals: instant but temporary smoothing, more substantive improvement over time, cost considerations, and tolerance for in-office procedures.
How to Choose the Best Wrinkle Filler for You
- Targeted area: Do you need all-over smoothing or spot treatment for deep creases?
- Desired longevity: Instant results for events, or longer-term change?
- Budget: Are you looking for a luxury splurge or a budget alternative?
- Sensitivity: Is your skin prone to irritation or reactions?
- Comfort level: Are you open to injectables or do you prefer needle-free options?
Dermatologist-Recommended Wrinkle Fillers of 2024
1. Doctor Babor Collagen-Peptide Derma Filler Serum
- Best for: Lightweight, all-over smoothing and hydration
This serum is a favorite among dermatologists for its blend of vegan collagen, low molecular weight hyaluronic acid, and peptides. It absorbs instantly, leaving no greasy residue, and works to fill in spaces between skin cells for a visibly plumper, smoother appearance. Multiple reviewers praise its water-like feel and fast plumping effect, making it ideal for both morning and evening routines.
- Key ingredients: Peptides, hyaluronic acid, ginseng extract, quinoa extract
- Best for: Hydration, fine line smoothing, all skin types
2. Peter Thomas Roth Instant FIRMx Temporary Face Tightener
- Best for: Immediate, dramatic tightening before events
Need to look lifted fast? This unique blend of silicates, seaweed extract, and vitamins delivers an immediate tightening effect, visibly smoothing wrinkles and sagging areas. The application requires practice; if not rubbed in thoroughly, it may leave a white cast. Nevertheless, users rave about the dramatic, though temporary, effects, describing their lines as 75% smoothed after use. Makeup may pill if applied too soon after this product, so follow directions closely.
- Key ingredients: Silicates, seaweed, vitamins B5, C, and E
- Best for: Instant results for special occasions
3. Ourself HA+ Replenishing Serum
- Best for: Deep hydration with high-tech skin penetration
This serum features “subtopical firming technology”—a proprietary blend that transports hyaluronic acid and peptides deeper into the skin. The combination helps to mimic the volumizing effect of an injectable without needles. Users highlight its lightweight texture, fast absorption, hydrating power, and suitability for sensitive skin. Many report noticeable reduction in fine lines and increased suppleness, making it a star under makeup and before moisturizer.
- Key ingredients: Hyaluronic acid, peptides, vitamin C, niacinamide
- Best for: Immediate and long-term plumping
4. Skinbetter Science InterFuse Intensive Treatment Lines
- Best for: Targeted wrinkle filling (eyes, smile lines, crow’s feet)
This intensive treatment is designed for pinpoint application—think forehead creases, 11’s, crow’s feet, and lines above the lip. Dermatologists and users alike praise its effectiveness in smoothing areas prone to deep wrinkles, leaving skin plump, hydrated, and visibly softened. Though on the pricier side, it’s highly regarded for achieving visible improvements in stubborn expression lines.
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- Key ingredients: Hyaluronic acid, peptides, vitamin C, amino acids
- Best for: Deep, targeted lines and rough texture
5. RoC Retinol Correxion Deep Wrinkle Night Cream
- Best for: Retinol-power smoothing with added glycolic acid
A long-time favorite, this night cream combines retinol—renowned for its cell turnover and anti-aging benefits—with glycolic acid for enhanced exfoliation and skin renewal. Over weeks, it helps reduce depth of wrinkles and fade dark spots. Glycerin and dimethicone deliver instant moisture to minimize irritation, while its affordable price point means it’s accessible for most routines. Note: Only use at night, as retinol and glycolic acid can increase sun sensitivity.
- Key ingredients: Retinol, glycolic acid, glycerin, dimethicone
- Best for: Overnight treatment, budget-friendly routines, uneven skin tone
6. Neutrogena Rapid Wrinkle Repair Retinol Moisturizer
- Best for: Affordable retinol and hyaluronic acid combo
This drugstore staple, recommended by dermatologists for its efficacy and gentle formulation, blends hydrating hyaluronic acid with retinol to tackle fine lines, wrinkles, and even dark spots. Suitable for sensitive skin and daily use (morning and night), it’s often cited as a fast-acting, smooth, and brightening choice—though users suggest regular exfoliation to avoid any pilling on the skin.
- Key ingredients: Retinol, hyaluronic acid
- Best for: All skin types, daily regimen, value-conscious shoppers
7. Alastin Skincare HA Immerse Serum
- Best for: Long-term plumping and moisture retention
This dermatologist-backed serum leverages the hydrating power of hyaluronic acid, alongside proprietary peptides, to create an immediate and enduring volumizing effect. Approved for even sensitive skin, the formula helps maintain optimal moisture levels, making wrinkles less pronounced with regular use. Reviewers particularly loved how smoothly it applies and its ability to make skin feel bouncier over several weeks.
- Key ingredients: Hyaluronic acid, peptides, antioxidants
- Best for: Dehydrated skin, mature skin with fine and deep lines
8. Juvéderm, RHA, and Restylane (Injectable Fillers)
- Best for: In-office, long-lasting wrinkle plumping
According to leading dermatologists, the most dramatic and long-lasting improvement in deep wrinkles often comes from injectable hyaluronic acid fillers. Brands like Juvéderm, RHA, and Restylane offer customized options for various areas (lips, cheeks, nasolabial folds, under-eyes). Results can last from six months up to two years, depending on the formula and location. Always consult a board-certified dermatologist or plastic surgeon to discuss goals, risks, costs, and suitability for your skin type.
- Key ingredients: Hyaluronic acid, crosslinked polymers (injectable gel)
- Best for: Deep lines, lost volume, instant transformations
9. L’Oréal Paris Revitalift Filler Hyaluronic Acid Serum
- Best for: Drugstore-priced hydrating and firming
This affordable serum capitalizes on the smoothing and plumping benefits of hyaluronic acid. It penetrates quickly and leaves skin looking visibly fuller, making it a popular pick among those seeking everyday, non-irritating wrinkle relief. Reviewers appreciate its lightweight feel and non-greasy finish, making it ideal for wearing under makeup or sunscreen.
- Key ingredients: Hyaluronic acid
- Best for: All skin types, layering in AM/PM regimens
Wrinkle Fillers Comparison Table
| Product | Type | Main Ingredients | Best For | Longevity |
|---|---|---|---|---|
| Doctor Babor Collagen-Peptide Derma Filler Serum | Topical | Peptides, Hyaluronic Acid | All-over smoothing | Short-term and long-term |
| Peter Thomas Roth Instant FIRMx Tightener | Topical | Silicates, Seaweed Extract | Immediate tightening | Temporary (hours) |
| Ourself HA+ Replenishing Serum | Topical | Hyaluronic Acid, Vitamin C | Deep hydration | Hours to days |
| Skinbetter Science InterFuse Intensive | Topical | Hyaluronic Acid, Peptides | Targeted wrinkles | Hours to days |
| RoC Retinol Correxion Night Cream | Topical | Retinol, Glycolic Acid | Overnight renewal | Weeks |
| Neutrogena Rapid Wrinkle Repair | Topical | Retinol, Hyaluronic Acid | Everyday prevention | Weeks |
| Alastin Skincare HA Immerse Serum | Topical | Hyaluronic Acid, Peptides | Long-term plumping | Ongoing use |
| Juvéderm, RHA, Restylane | Injectable | Hyaluronic Acid Gels | Deep lines, lost volume | 6-24 months |
| L’Oréal Paris Revitalift Filler Serum | Topical | Hyaluronic Acid | Affordable hydrating | Daily use |
Key Ingredients to Look For
- Hyaluronic Acid: A powerful humectant, drawing water into the skin for immediate plumping and hydration.
- Peptides: Support collagen production and improve skin firmness, helping reduce wrinkle depth.
- Retinol: Boosts cell turnover, minimizes fine lines, and refines texture over time.
- Vitamin C: A brightening antioxidant, supporting collagen synthesis and helping to fade discoloration.
- Silicates: Temporarily tighten and smooth skin, delivering instant—but short-term—results.
- Niacinamide: Brightens, soothes, and supports the skin barrier while reducing hyperpigmentation.
How Do Injectables Compare to Topical Wrinkle Fillers?
| Aspect | Injectable Fillers | Topical Fillers |
|---|---|---|
| Effect Duration | 6-24 months | Hours to days |
| Downtime | Minimal (may have swelling/bruising) | None |
| Invasiveness | Involves needles | Non-invasive |
| Visible Results | Dramatic, immediate | Subtle to moderate |
| Cost | High | Low to moderate |
Safety Tips and Advice for Using Wrinkle Fillers
- Injectables should only be performed by licensed dermatologists or plastic surgeons in accredited clinics. Always research your provider and ask to see before-and-after photos.
- Topical products are safest for at-home use, but always patch test new formulas if you have sensitive skin.
- Use sun protection daily when using retinol, glycolic acid, or other exfoliants, as these ingredients increase UV sensitivity.
- Avoid mixing multiple actives unless advised by a professional, to prevent irritation.
- Gradually introduce retinol and exfoliating acids to build up your skin’s tolerance.
Wrinkle Fillers: Frequently Asked Questions
What’s the difference between a wrinkle filler and a wrinkle cream?
Wrinkle fillers, whether topical or injectable, are formulated specifically to fill and plump lines for an immediate smoothing effect. Wrinkle creams, on the other hand, generally focus on long-term improvement of skin texture and overall health.
Are wrinkle fillers safe for sensitive skin?
Many topical wrinkle fillers are formulated without fragrances or common irritants, making them safe for sensitive skin. Patch testing is always recommended.
Can I use a wrinkle filler every day?
Most topical fillers can be used daily, often twice a day. Always verify recommendations for active ingredients—retinol and acids may require a slower introduction.
How long do injectables last?
Results from injectable fillers can last from 6 to 24 months, depending on the location treated, product used, and individual metabolism.
Is there a topical that works as well as an injectable?
Topicals can visibly reduce the appearance of fine lines, but only injectables deliver dramatic, longer-lasting filling for deep wrinkles. However, newer serums now offer “subtopical” technology for more impressive plumping than previous generations.
Tips for Maximizing Results with Wrinkle Fillers
- Keep skin hydrated by drinking water, using gentle cleansers, and layering serums under moisturizers.
- Protect your investment in injectables or topical actives by wearing sunscreen daily.
- Practice consistent application—results build over time for both topicals and injectables.
- Consult a dermatologist or licensed injector for a tailored plan, and never compromise on product or provider quality for a deal.
Key Takeaways
- Hyaluronic acid and peptides are essential ingredients for plumping and smoothing lines.
- Injectables deliver the most dramatic and lasting results for deep wrinkles.
- Topical wrinkle fillers are an excellent option for instant, visible improvement with no downtime, especially when used consistently.
- Always work with reputable professionals for in-office procedures and maintain daily skincare habits to maximize results.
References
- https://www.womenshealthmag.com/beauty/g45035438/best-wrinkle-creams/
- https://www.cosmopolitan.com/style-beauty/beauty/g45306481/best-wrinkle-filler/
- https://www.cosmopolitan.com/style-beauty/beauty/a61927593/notox-needle-free-trend/
- https://www.aol.com/cosmo-exclusive-injectables-ever-look-142400202.html
- https://www.michelegreenmd.com/press-coverage/dr-green-talks-about-over-the-counter-wrinkle-fillers
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