20 Best Chemical Exfoliants for Every Skin Type and Concern
Discover the top chemical exfoliants for sensitive, acne-prone, oily, and dry skin, featuring expert-approved picks and tips for a radiant complexion.

Chemical exfoliants are a transformative addition to any skincare routine, offering smoother, brighter, and clearer skin. With expertly curated options and nuanced information about acids, this guide breaks down the science, top picks, and FAQs so you can uncover your healthiest complexion yet.
What Are Chemical Exfoliants?
Chemical exfoliants are skincare formulas that use acids to dissolve the bonds (the adhesive “glue”) between dead skin cells on the skin’s surface, promoting their removal for a fresh and revitalized appearance. Unlike physical scrubs, which may cause microtears or irritation, chemical exfoliants offer a more gentle, effective solution to cell turnover and radiance.
- AHAs (Alpha Hydroxy Acids): Water-soluble acids derived from fruit; ideal for dry, oily, or normal skin.
- BHAs (Beta Hydroxy Acids): Oil-soluble acids, best for acne-prone and congested skin.
- PHAs (Polyhydroxy Acids): Larger, gentler molecules ideal for sensitive skin types.
These ingredients stimulate cell turnover to help fade dark spots, smooth texture, brighten hyperpigmentation, and minimize pore appearance.
Manual vs Chemical Exfoliation
Manual or physical exfoliants—like scrubs and brushes—may lead to microtears, inflammation, and even collagen loss. By contrast, chemical exfoliants penetrate deeply and activate cell turnover for improved skin texture and radiance. Key tips for use include:
- Start slow; use chemical exfoliants 2-3 times a week, then gradually increase.
- Apply at night after cleansing.
- Always follow with moisturizer.
- Avoid overuse; excessive application can cause irritation or dryness.
Types of Chemical Exfoliants
Alpha Hydroxy Acids (AHAs)
- How they work: Remove dead skin cells, brighten tone, and smooth rough texture while acting as humectants for hydration.
- Common AHAs: Glycolic acid, lactic acid, malic acid, tartaric acid, mandelic acid.
- Best for: Dry, oily, or normal skin types; effective for treating hyperpigmentation, bumpy texture, and fine lines.
- Gentle Options: Low-dose lactic, malic, and mandelic acids can suit sensitive skin.
Beta Hydroxy Acids (BHAs)
- How they work: Oil-soluble acts deep within pores to clear congestion and blackheads.
- Common BHA: Salicylic acid.
- Best for: Oily and acne-prone skin; excellent for unclogging pores and treating breakouts.
Polyhydroxy Acids (PHAs)
- How they work: Large, gentle molecules exfoliate dead cells while hydrating, making them perfect for sensitive types.
- Common PHAs: Gluconolactone, lactobionic acid.
- Best for: Sensitive and dry skin types; ideal for those who cannot tolerate AHAs or BHAs.
Who Should Use Chemical Exfoliants?
Chemical exfoliants are suitable for a wide range of skin concerns and types:
- Dry Skin: AHAs and PHAs to hydrate and brighten.
- Oily/Acne-Prone Skin: BHAs to clear pores and prevent breakouts.
- Sensitive Skin: Low-dose lactic acid, mandelic acid, or PHAs to exfoliate gently.
- Normal Skin: All acid types, adjusted for individual needs.
The 20 Best Chemical Exfoliants of 2025
From dermatologist-recommended classics to innovative newcomers, here are the top chemical exfoliants for every skin type and concern:
- Best Overall: Dr. Dennis Gross Alpha Beta Universal Daily Peel
Blend of AHAs, BHAs, vitamin C, and retinol to smooth fine lines, minimize pores, and brighten. - Best for Dry Skin: Neutrogena Skin Perfecting Daily Liquid Exfoliant
PHAs, AHAs, and hyaluronic acid smooth texture and hydrate without irritation. - Best Serum: Shani Darden Skin Care Lactic Acid Exfoliating Serum
Gentle blend of lactic acid and gluconolactone to resurface overnight. - Best with BHAs: Paula’s Choice Skin Perfecting 2% BHA Liquid Exfoliant
Salicylic acid targets blackheads, congested pores, and excess oil. - Best for Acne-Prone Skin: Tula Breakout Breakthrough Acne Maximum Strength Biodegradable Toner Pads
Effective exfoliation and targeted acne-fighting ingredients. - Best for Hyperpigmentation: Hyper Skin Fade and Glow AHA Mask
Brightens, fades dark spots, and evens skin tone. - Best for Sensitive Skin: Cetaphil Healthy Radiance PHA Cleanser
PHAs offer gentle exfoliation suitable for sensitivity and dryness. - Best for Body: Farmacy Honeymoon Glow Body 12% AHA/BHA Resurfacing Body Serum
High-strength blend for smooth, even skin on arms, legs, elbows, and more.
Complete List of Top Chemical Exfoliants:
- Dr. Dennis Gross Skincare Alpha Beta Universal Daily Peel
- Neutrogena Skin Perfecting Daily Liquid Exfoliant
- The Ordinary AHA 30% + BHA 2% Peeling Solution
- Shani Darden Skin Care Lactic Acid Exfoliating Serum
- Paula’s Choice Skin Perfecting 2% BHA Liquid Exfoliant
- Tula Breakout Breakthrough Acne Toner Pads
- Hyper Skin Fade and Glow AHA Mask
- Cetaphil Healthy Radiance PHA Cleanser
- Farmacy Honeymoon Glow Body Resurfacing Serum
- Glow Recipe Watermelon Glow PHA+BHA Toner
- Murad Replenishing Multi-Acid Peel
- Glossier Solution Exfoliating Skin Perfector
- Pixi Glow Tonic
- Sunday Riley Good Genes All-In-One Lactic Acid Treatment
- Ktchn Apothecary Hydrate + Glow Gentle Daily Exfoliant
- Biossance Squalane + Lactic Acid Resurfacing Night Serum
- Versed Weekend Glow Daily Brightening Solution
- OLEHENRIKSEN Glow2OH Dark Spot Toner
- Drunk Elephant T.L.C. Framboos Glycolic Night Serum
- Allies of Skin Mandelic Pigmentation Corrector Night Serum
How to Incorporate Chemical Exfoliants Into Your Routine
- Apply chemical exfoliants after cleansing, usually at night.
- Begin with 2-3 times a week, then adjust as skin builds tolerance.
- Follow with a hydrating, gentle moisturizer.
- Never skip broad-spectrum sunscreen the next day, as exfoliated skin is more sun-sensitive.
Key Ingredients in Top Chemical Exfoliants
Ingredient | Type | Special Benefit |
---|---|---|
Glycolic Acid | AHA | Deep exfoliation, fades hyperpigmentation, smoothes texture |
Lactic Acid | AHA | Gentle, hydrating, boosts radiance |
Mandelic Acid | AHA | Mild, suitable for sensitive skin |
Salicylic Acid | BHA | Clears pores, treats acne, tackles blackheads |
Gluconolactone | PHA | Super gentle, hydrates, suitable for sensitivity |
Expert Tips for Safe Exfoliation
- Do not combine chemical exfoliants with harsh physical scrubs.
- Avoid layering multiple exfoliants simultaneously; stick to one formula for best results.
- If skin becomes red or irritated, reduce usage or switch to a gentler acid.
- Consult a dermatologist for personalized recommendations, especially if dealing with sensitive, reactive, or acne-prone skin.
FAQs About Chemical Exfoliants
Q: What makes chemical exfoliants superior to physical scrubs?
A: Chemical exfoliants dissolve cellular bonds seamlessly and minimize the risk of abrasions or microtears, resulting in more consistent results and improved skin health.
Q: Are chemical exfoliants suitable for sensitive skin?
A: Yes. Low-dose lactic, mandelic acid, and PHAs provide gentle exfoliation with hydration, making them ideal for sensitive skin.
Q: How often should I use a chemical exfoliant?
A: Begin with 2-3 times weekly at night, observe how your skin responds, and increase frequency as tolerated to avoid irritation.
Q: Can I use chemical exfoliants on my body?
A: Absolutely. Body-specific formulas like Farmacy Honeymoon Glow Body Serum smooth rough elbows, knees, and legs for even, radiant skin.
Q: What are the signs of over-exfoliation?
A: Redness, sensitivity, peeling, and dryness can indicate excessive exfoliation. Reduce frequency immediately if these occur and apply soothing moisturizer.
Q: Do chemical exfoliants cause sun sensitivity?
A: Yes. Newly exfoliated skin is more vulnerable to UV rays. Always follow application with a broad-spectrum sunscreen during the day to prevent damage.
Summary Table: Choosing the Right Chemical Exfoliant
Skin Type | Recommended Exfoliant | Common Active Ingredients |
---|---|---|
Dry | AHAs, PHAs | Lactic acid, glycolic acid, gluconolactone |
Oily/Acne-Prone | BHAs | Salicylic acid |
Sensitive | Low-dose AHAs, PHAs | Mandelic acid, gluconolactone |
Normal | AHAs, BHAs, PHAs | Blend of acids as desired |
Conclusion
Chemical exfoliation is a high-impact skincare solution for anyone looking to reveal brighter, smoother, and healthier skin. From facial serums to body treatments, selecting the right acid or blend based on your skin type and goals is key. With thoughtful use and expert advice, you’ll experience the transformative results these top exfoliants provide.
Frequently Asked Questions (FAQs)
Q: Can chemical exfoliants help with acne?
A: Yes, BHAs like salicylic acid penetrate pores to effectively decrease breakouts and congestion.
Q: Are chemical exfoliants safe for daily use?
A: Gentler formulas like lactic acid and PHAs may be used daily, but most should begin 2-3 times weekly before building up gradually.
Q: Should I use sunscreen after exfoliating?
A: Always use broad-spectrum sunscreen after chemical exfoliation to protect your sensitive skin from UV damage.
Q: What’s best for body exfoliation?
A: Higher-strength blends with AHAs and BHAs, like Farmacy Honeymoon Glow Body Serum, are excellent for rough or uneven body skin.
References
- https://www.cosmopolitan.com/style-beauty/beauty/g39411878/best-chemical-exfoliants/
- https://www.doctorrogers.com/blogs/blog/one-minute-clinic-exfoliation-101
- https://www.cosmopolitan.com/style-beauty/beauty/a64938060/best-at-home-chemical-peels/
- https://www.cosmopolitanme.com/beauty/chemical-exfoliants-glycolic-lactic
- https://drophelia.com/blogs/news-and-views/in-the-news-cosmopolitan
- https://www.cosmopolitanme.com/beauty/polyhydroxy-acid-101-your-guide-to-the-exfoliant
- https://www.turnerdermatology.com/newmedia/2024/1/3/cosmopolitan-19-best-face-exfoliators-tested-and-reviewed-for-2024
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