20 Best Chemical Exfoliants for Every Skin Type and Concern

Discover the top chemical exfoliants for sensitive, acne-prone, oily, and dry skin, featuring expert-approved picks and tips for a radiant complexion.

By Sneha Tete, Integrated MA, Certified Relationship Coach
Created on

Chemical exfoliants are a transformative addition to any skincare routine, offering smoother, brighter, and clearer skin. With expertly curated options and nuanced information about acids, this guide breaks down the science, top picks, and FAQs so you can uncover your healthiest complexion yet.

What Are Chemical Exfoliants?

Chemical exfoliants are skincare formulas that use acids to dissolve the bonds (the adhesive “glue”) between dead skin cells on the skin’s surface, promoting their removal for a fresh and revitalized appearance. Unlike physical scrubs, which may cause microtears or irritation, chemical exfoliants offer a more gentle, effective solution to cell turnover and radiance.

  • AHAs (Alpha Hydroxy Acids): Water-soluble acids derived from fruit; ideal for dry, oily, or normal skin.
  • BHAs (Beta Hydroxy Acids): Oil-soluble acids, best for acne-prone and congested skin.
  • PHAs (Polyhydroxy Acids): Larger, gentler molecules ideal for sensitive skin types.

These ingredients stimulate cell turnover to help fade dark spots, smooth texture, brighten hyperpigmentation, and minimize pore appearance.

Manual vs Chemical Exfoliation

Manual or physical exfoliants—like scrubs and brushes—may lead to microtears, inflammation, and even collagen loss. By contrast, chemical exfoliants penetrate deeply and activate cell turnover for improved skin texture and radiance. Key tips for use include:

  • Start slow; use chemical exfoliants 2-3 times a week, then gradually increase.
  • Apply at night after cleansing.
  • Always follow with moisturizer.
  • Avoid overuse; excessive application can cause irritation or dryness.

Types of Chemical Exfoliants

Alpha Hydroxy Acids (AHAs)

  • How they work: Remove dead skin cells, brighten tone, and smooth rough texture while acting as humectants for hydration.
  • Common AHAs: Glycolic acid, lactic acid, malic acid, tartaric acid, mandelic acid.
  • Best for: Dry, oily, or normal skin types; effective for treating hyperpigmentation, bumpy texture, and fine lines.
  • Gentle Options: Low-dose lactic, malic, and mandelic acids can suit sensitive skin.

Beta Hydroxy Acids (BHAs)

  • How they work: Oil-soluble acts deep within pores to clear congestion and blackheads.
  • Common BHA: Salicylic acid.
  • Best for: Oily and acne-prone skin; excellent for unclogging pores and treating breakouts.

Polyhydroxy Acids (PHAs)

  • How they work: Large, gentle molecules exfoliate dead cells while hydrating, making them perfect for sensitive types.
  • Common PHAs: Gluconolactone, lactobionic acid.
  • Best for: Sensitive and dry skin types; ideal for those who cannot tolerate AHAs or BHAs.

Who Should Use Chemical Exfoliants?

Chemical exfoliants are suitable for a wide range of skin concerns and types:

  • Dry Skin: AHAs and PHAs to hydrate and brighten.
  • Oily/Acne-Prone Skin: BHAs to clear pores and prevent breakouts.
  • Sensitive Skin: Low-dose lactic acid, mandelic acid, or PHAs to exfoliate gently.
  • Normal Skin: All acid types, adjusted for individual needs.

The 20 Best Chemical Exfoliants of 2025

From dermatologist-recommended classics to innovative newcomers, here are the top chemical exfoliants for every skin type and concern:

  • Best Overall: Dr. Dennis Gross Alpha Beta Universal Daily Peel
    Blend of AHAs, BHAs, vitamin C, and retinol to smooth fine lines, minimize pores, and brighten.
  • Best for Dry Skin: Neutrogena Skin Perfecting Daily Liquid Exfoliant
    PHAs, AHAs, and hyaluronic acid smooth texture and hydrate without irritation.
  • Best Serum: Shani Darden Skin Care Lactic Acid Exfoliating Serum
    Gentle blend of lactic acid and gluconolactone to resurface overnight.
  • Best with BHAs: Paula’s Choice Skin Perfecting 2% BHA Liquid Exfoliant
    Salicylic acid targets blackheads, congested pores, and excess oil.
  • Best for Acne-Prone Skin: Tula Breakout Breakthrough Acne Maximum Strength Biodegradable Toner Pads
    Effective exfoliation and targeted acne-fighting ingredients.
  • Best for Hyperpigmentation: Hyper Skin Fade and Glow AHA Mask
    Brightens, fades dark spots, and evens skin tone.
  • Best for Sensitive Skin: Cetaphil Healthy Radiance PHA Cleanser
    PHAs offer gentle exfoliation suitable for sensitivity and dryness.
  • Best for Body: Farmacy Honeymoon Glow Body 12% AHA/BHA Resurfacing Body Serum
    High-strength blend for smooth, even skin on arms, legs, elbows, and more.

Complete List of Top Chemical Exfoliants:

  1. Dr. Dennis Gross Skincare Alpha Beta Universal Daily Peel
  2. Neutrogena Skin Perfecting Daily Liquid Exfoliant
  3. The Ordinary AHA 30% + BHA 2% Peeling Solution
  4. Shani Darden Skin Care Lactic Acid Exfoliating Serum
  5. Paula’s Choice Skin Perfecting 2% BHA Liquid Exfoliant
  6. Tula Breakout Breakthrough Acne Toner Pads
  7. Hyper Skin Fade and Glow AHA Mask
  8. Cetaphil Healthy Radiance PHA Cleanser
  9. Farmacy Honeymoon Glow Body Resurfacing Serum
  10. Glow Recipe Watermelon Glow PHA+BHA Toner
  11. Murad Replenishing Multi-Acid Peel
  12. Glossier Solution Exfoliating Skin Perfector
  13. Pixi Glow Tonic
  14. Sunday Riley Good Genes All-In-One Lactic Acid Treatment
  15. Ktchn Apothecary Hydrate + Glow Gentle Daily Exfoliant
  16. Biossance Squalane + Lactic Acid Resurfacing Night Serum
  17. Versed Weekend Glow Daily Brightening Solution
  18. OLEHENRIKSEN Glow2OH Dark Spot Toner
  19. Drunk Elephant T.L.C. Framboos Glycolic Night Serum
  20. Allies of Skin Mandelic Pigmentation Corrector Night Serum

How to Incorporate Chemical Exfoliants Into Your Routine

  • Apply chemical exfoliants after cleansing, usually at night.
  • Begin with 2-3 times a week, then adjust as skin builds tolerance.
  • Follow with a hydrating, gentle moisturizer.
  • Never skip broad-spectrum sunscreen the next day, as exfoliated skin is more sun-sensitive.

Key Ingredients in Top Chemical Exfoliants

IngredientTypeSpecial Benefit
Glycolic AcidAHADeep exfoliation, fades hyperpigmentation, smoothes texture
Lactic AcidAHAGentle, hydrating, boosts radiance
Mandelic AcidAHAMild, suitable for sensitive skin
Salicylic AcidBHAClears pores, treats acne, tackles blackheads
GluconolactonePHASuper gentle, hydrates, suitable for sensitivity

Expert Tips for Safe Exfoliation

  • Do not combine chemical exfoliants with harsh physical scrubs.
  • Avoid layering multiple exfoliants simultaneously; stick to one formula for best results.
  • If skin becomes red or irritated, reduce usage or switch to a gentler acid.
  • Consult a dermatologist for personalized recommendations, especially if dealing with sensitive, reactive, or acne-prone skin.

FAQs About Chemical Exfoliants

Q: What makes chemical exfoliants superior to physical scrubs?

A: Chemical exfoliants dissolve cellular bonds seamlessly and minimize the risk of abrasions or microtears, resulting in more consistent results and improved skin health.

Q: Are chemical exfoliants suitable for sensitive skin?

A: Yes. Low-dose lactic, mandelic acid, and PHAs provide gentle exfoliation with hydration, making them ideal for sensitive skin.

Q: How often should I use a chemical exfoliant?

A: Begin with 2-3 times weekly at night, observe how your skin responds, and increase frequency as tolerated to avoid irritation.

Q: Can I use chemical exfoliants on my body?

A: Absolutely. Body-specific formulas like Farmacy Honeymoon Glow Body Serum smooth rough elbows, knees, and legs for even, radiant skin.

Q: What are the signs of over-exfoliation?

A: Redness, sensitivity, peeling, and dryness can indicate excessive exfoliation. Reduce frequency immediately if these occur and apply soothing moisturizer.

Q: Do chemical exfoliants cause sun sensitivity?

A: Yes. Newly exfoliated skin is more vulnerable to UV rays. Always follow application with a broad-spectrum sunscreen during the day to prevent damage.

Summary Table: Choosing the Right Chemical Exfoliant

Skin TypeRecommended ExfoliantCommon Active Ingredients
DryAHAs, PHAsLactic acid, glycolic acid, gluconolactone
Oily/Acne-ProneBHAsSalicylic acid
SensitiveLow-dose AHAs, PHAsMandelic acid, gluconolactone
NormalAHAs, BHAs, PHAsBlend of acids as desired

Conclusion

Chemical exfoliation is a high-impact skincare solution for anyone looking to reveal brighter, smoother, and healthier skin. From facial serums to body treatments, selecting the right acid or blend based on your skin type and goals is key. With thoughtful use and expert advice, you’ll experience the transformative results these top exfoliants provide.

Frequently Asked Questions (FAQs)

Q: Can chemical exfoliants help with acne?

A: Yes, BHAs like salicylic acid penetrate pores to effectively decrease breakouts and congestion.

Q: Are chemical exfoliants safe for daily use?

A: Gentler formulas like lactic acid and PHAs may be used daily, but most should begin 2-3 times weekly before building up gradually.

Q: Should I use sunscreen after exfoliating?

A: Always use broad-spectrum sunscreen after chemical exfoliation to protect your sensitive skin from UV damage.

Q: What’s best for body exfoliation?

A: Higher-strength blends with AHAs and BHAs, like Farmacy Honeymoon Glow Body Serum, are excellent for rough or uneven body skin.

Sneha Tete
Sneha TeteBeauty & Lifestyle Writer
Sneha is a relationships and lifestyle writer with a strong foundation in applied linguistics and certified training in relationship coaching. She brings over five years of writing experience to thebridalbox, crafting thoughtful, research-driven content that empowers readers to build healthier relationships, boost emotional well-being, and embrace holistic living.

Read full bio of Sneha Tete